Florida leads U.S. residential real estate vacancy rates, with six metro areas ranking highest nationally. Cape Coral-Fort Myers tops at 38.7%, followed by North Port-Bradenton-Sarasota (23.7%) and Tampa-St. Petersburg-Clearwater (13.3%). Orlando and Sarasota saw notable vacancy declines, suggesting rising demand. Florida also faces high commercial office vacancies, with Orlando, Tampa, and Miami among the top cities for empty office spaces.